Download movie file (mov. file, 9300 KB)
All rights reserved. Use of the movie should refer to Nyblom et al. 2013.
Please refer to the following papers for further details:
Crystal structure of Na+, K(+)-ATPase in the Na(+)-bound state.
Nyblom M, Poulsen H, Gourdon P, Reinhard L, Andersson M, Lindahl E, Fedosova N, Nissen P.
Science. 2013 Oct 4;342(6154):123-7.
Structures and characterization of digoxin- and bufalin-bound Na+,K+-ATPase compared with the ouabain-bound complex.
Laursen M, Gregersen JL, Yatime L, Nissen P, Fedosova NU.
Proc Natl Acad Sci U S A. 2015 Feb 10;112(6):1755-60.
Crystal structure of the high-affinity Na+K+-ATPase-ouabain complex with Mg2+ bound in the cation binding site.
Laursen M, Yatime L, Nissen P, Fedosova NU.
Proc Natl Acad Sci U S A. 2013 Jul 2;110(27):10958-63.
Crystal structure of the sodium-potassium pump.
Morth JP, Pedersen BP, Toustrup-Jensen MS, Sørensen TL, Petersen J, Andersen JP, Vilsen B, Nissen P.
Nature. 2007 Dec 13;450(7172):1043-9.
How to Compare, Analyze, and Morph Between Crystal Structures of Different Conformations : The P-Type ATPase Example.
Karlsen JL, Bublitz M.
Methods in molecular biology (Clifton, N.J.), Vol. 1377, 2016, s. 523-39.
Download movie file (mov. file, 5557 KB)
All rights reserved. Use of the movie should refer to Bublitz et al. 2013.
Please refer to the following papers for further details:
How to Compare, Analyze, and Morph Between Crystal Structures of Different Conformations : The P-Type ATPase Example.
Karlsen JL, Bublitz M.
Methods in molecular biology (Clifton, N.J.), Vol. 1377, 2016, s. 523-39.
Ion pathways in the sarcoplasmic reticulum Ca2+-ATPase.
Bublitz M, Musgaard M, Poulsen H, Thøgersen L, Olesen C, Schiøtt B, Morth JP, Møller JV, Nissen P.
J Biol Chem. 2013 Apr 12;288(15):10759-65.
The sarcolipin-bound calcium pump stabilizes calcium sites exposed to the cytoplasm.
Winther AM, Bublitz M, Karlsen JL, Møller JV, Hansen JB, Nissen P, Buch-Pedersen MJ.
Nature. 2013 Mar 14;495(7440):265-9.
Mutual adaptation of a membrane protein and its lipid bilayer during conformational changes.
Sonntag Y, Musgaard M, Olesen C, Schiøtt B, Møller JV, Nissen P, Thøgersen L.
Nat Commun. 2011;2:304.
The sarcoplasmic Ca2+-ATPase: design of a perfect chemi-osmotic pump.
Møller JV, Olesen C, Winther AM, Nissen P.
Q Rev Biophys. 2010 Nov;43(4):501-66.
Cyclopiazonic acid is complexed to a divalent metal ion when bound to the sarcoplasmic reticulum Ca2+-ATPase.
Laursen M, Bublitz M, Moncoq K, Olesen C, Møller JV, Young HS, Nissen P, Morth JP.
J Biol Chem. 2009 May 15;284(20):13513-8.
Crystal structure of D351A and P312A mutant forms of the mammalian sarcoplasmic reticulum Ca(2+) -ATPase reveals key events in phosphorylation and Ca(2+) release.
Marchand A, Winther AM, Holm PJ, Olesen C, Montigny C, Arnou B, Champeil P, Clausen JD, Vilsen B, Andersen JP, Nissen P, Jaxel C, Møller JV, le Maire M.
J Biol Chem. 2008 May 23;283(21):14867-82.
The structural basis of calcium transport by the calcium pump.
Olesen C, Picard M, Winther AM, Gyrup C, Morth JP, Oxvig C, Møller JV, Nissen P.
Nature. 2007 Dec 13;450(7172):1036-42.
Modulatory and catalytic modes of ATP binding by the calcium pump.
Jensen AM, Sørensen TL, Olesen C, Møller JV, Nissen P.
EMBO J. 2006 Jun 7;25(11):2305-14. Epub 2006 May 18.
Dephosphorylation of the calcium pump coupled to counterion occlusion.
Olesen C, Sørensen TL, Nielsen RC, Møller JV, Nissen P.
Science. 2004 Dec 24;306(5705):2251-5.
Phosphoryl transfer and calcium ion occlusion in the calcium pump.
Sørensen TL, Møller JV, Nissen P.
Science. 2004 Jun 11;304(5677):1672-5.
Download movie file (mov. file, 14,783 KB)
All rights reserved. Use of the movie should refer to Bublitz et al. 2013.
Please refer to the following papers for further details:
How to Compare, Analyze, and Morph Between Crystal Structures of Different Conformations : The P-Type ATPase Example.
Karlsen JL, Bublitz M.
Methods in molecular biology (Clifton, N.J.), Vol. 1377, 2016, s. 523-39.
Ion pathways in the sarcoplasmic reticulum Ca2+-ATPase.
Bublitz M, Musgaard M, Poulsen H, Thøgersen L, Olesen C, Schiøtt B, Morth JP, Møller JV, Nissen P.
J Biol Chem. 2013 Apr 12;288(15):10759-65.
The sarcolipin-bound calcium pump stabilizes calcium sites exposed to the cytoplasm.
Winther AM, Bublitz M, Karlsen JL, Møller JV, Hansen JB, Nissen P, Buch-Pedersen MJ.
Nature. 2013 Mar 14;495(7440):265-9.
Mutual adaptation of a membrane protein and its lipid bilayer during conformational changes.
Sonntag Y, Musgaard M, Olesen C, Schiøtt B, Møller JV, Nissen P, Thøgersen L.
Nat Commun. 2011;2:304.
The sarcoplasmic Ca2+-ATPase: design of a perfect chemi-osmotic pump.
Møller JV, Olesen C, Winther AM, Nissen P.
Q Rev Biophys. 2010 Nov;43(4):501-66.
Cyclopiazonic acid is complexed to a divalent metal ion when bound to the sarcoplasmic reticulum Ca2+-ATPase.
Laursen M, Bublitz M, Moncoq K, Olesen C, Møller JV, Young HS, Nissen P, Morth JP.
J Biol Chem. 2009 May 15;284(20):13513-8.
Crystal structure of D351A and P312A mutant forms of the mammalian sarcoplasmic reticulum Ca(2+) -ATPase reveals key events in phosphorylation and Ca(2+) release.
Marchand A, Winther AM, Holm PJ, Olesen C, Montigny C, Arnou B, Champeil P, Clausen JD, Vilsen B, Andersen JP, Nissen P, Jaxel C, Møller JV, le Maire M.
J Biol Chem. 2008 May 23;283(21):14867-82.
The structural basis of calcium transport by the calcium pump.
Olesen C, Picard M, Winther AM, Gyrup C, Morth JP, Oxvig C, Møller JV, Nissen P.
Nature. 2007 Dec 13;450(7172):1036-42.
Modulatory and catalytic modes of ATP binding by the calcium pump.
Jensen AM, Sørensen TL, Olesen C, Møller JV, Nissen P.
EMBO J. 2006 Jun 7;25(11):2305-14. Epub 2006 May 18.
Dephosphorylation of the calcium pump coupled to counterion occlusion.
Olesen C, Sørensen TL, Nielsen RC, Møller JV, Nissen P.
Science. 2004 Dec 24;306(5705):2251-5.
Phosphoryl transfer and calcium ion occlusion in the calcium pump.
Sørensen TL, Møller JV, Nissen P.
Science. 2004 Jun 11;304(5677):1672-5.
