DANDRITE Topical Seminar: Examining disease-related human membrane protein (ABCG2, PMCA4b, SLC6A8) variants in cellular models

At the Membrane Transporter Laboratory, our research focuses on finding and characterizing naturally occurring variants in membrane proteins that may increase disease susceptibility or lead to diseases due to altered expression and function of the membrane protein. During my PhD studies, I worked on three key membrane transporters: the ABCG2 multidrug transporter, the PMCA4b calcium pump and the SLC6A8 creatine transporter.