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Publication in EMBO Molecular Medicine by Mette Richner and Christian B. Vægter

The findings in the paper entitled “A high-affinity, bivalent PDZ domain inhibitor complexes PICK1 to alleviate neuropathic pain” were made in collaboration between DANDRITE-affiliated researchers Christian B. Vægter and Mette Richner and researchers from University of Copenhagen.

Data in the picture show: “Neuropathic pain is characterized by hypersensitivity to temperature and touch as well as spontaneous outburst of pain. This study identifies a peptide that can inhibit PICK1 and thereby interfere with insertion of excess glutamate receptor underlying the hypersensitivity in neuropathic pain.”

 

Link to full article:
https://www.embopress.org/doi/full/10.15252/emmm.201911248