"My goal is to learn more about and improve blood flow in the brain"
Vladimir Matchkov from the Department of Biomedicine has received a grant of DKK 2,877,840 from the Independent Research Fund Denmark's Council for Health and Disease for a new brain research project.
In a new research project, Professor Vladimir Matchkov will examine the role of the calcium-activated chloride channel in blood vessels in the brain, and whether it has significance for brain function and blood flow when people suffer a stroke.
"We’ve shown that the calcium-activated chloride channel is crucial for the oscillations in intestinal blood vessels. However, it is unclear whether the same channel forms oscillations in the blood vessels in the brain, because these blood vessels have different properties. Therefore, we’re using genetically modified mice without a chloride channel to investigate the channel's importance for brain function. We’re doing this using advanced brain imaging," says Vladimir Matchkov.
The aim of the research project is to learn more about and improve blood flow in the brain in connection with diseases such as apoplexy, Alzheimer's, diabetes and high blood pressure. The project combines neuroscience and circulatory physiology and is being carried out in collaboration with Professor Anna Devor from Boston University.
Contact
Professor, DMSc and PhD Vladimir Matchkov
Aarhus University, Department of Biomedicine
Mobile: +45 21 83 49 82
Mail: vvm@biomed.au.dk