Joseph Lyons studies how lipid imbalance can cause disease
In June 2020, Joseph Lyons was appointed one of the Lundbeck Foundation Fellows 2020, and video interviews with the awardees have now been published. The grant enables Joseph Lyons to establish his own research group to study lipid transport and homeostasis for the next five years at the Department of Molecular Biology and Genetics/DANDRITE, Aarhus University.
Lipid asymmetry in the cells of the human body is important for a wide variety of basic biological processes and is generated and regulated by specific lipid transport machinery. Dysfunction in these transporters has a significant impact on human cell biology, with growing evidence indicating a role in neurological diseases such as Parkinson’s and Alzheimer’s disease.
Using cryo-electron microscopy, Joseph Lyons will study how lipid transport works at the atomic level.