Aarhus University Seal

Foteini Karapanagioti is visiting student in Poul Nissen's group

During her visit Foteini Karapanagioti will be investigating the effects of arrythmogenic calmodulin mutations on the regulation of cardiac plasma membrane Ca2+ ATPase. She is visiting master student from Aalborg University and will be visiting for ½ year.

The aim of the project is to investigate the structural changes of arrhythmic calmodulin mutations and the effects on the binding to and regulation of the cardiac Plasma Membrane Ca2+ ATPase (PMCA) pump. The acquired data will give an insight on the involvement of PMCA dysregulation in the mechanism of calmodulin mutation induced heart arrhythmia and sudden cardiac death.