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First ever GWAS of bedwetting published by Jane Hvarregaard Christensen Lab

The paper reports two genome-wide significant loci and potential risk genes with inherent roles in neurodevelopment including SIM1 and PRDM13. You can read more and find link to the article here.

Manhattan-plot of first ever GWAS of bedwetting.

The study also finds that common genetic variants explain 25-30% of the risk and that polygenic risk for ADHD is associated with bedwetting. The paper is published in The Lancet Child and Adolescent Health. You can read the paper here.