PD is one of the most common neurodegenerative disorders, not only causing movement difficulties but also affecting patients in less visible ways, such as depression, often years before motor symptoms appear or a diagnosis is made.

Frederik’s project will explore how the immune system contributes to these early disease symptoms. Using a cutting-edge Parkinson’s disease model, he will study the brain’s resident immune cells, called microglia, and investigate how they communicate with peripheral immune cells, such as T cells. By manipulating microglia activity and their interactions with T cells, Frederik aims to understand how these immune processes influence the progression of the disease.

Through his research, Frederik hopes to shed light on early-stage Parkinson’s pathology and contribute to the development of interventions that could act before debilitating symptoms emerge. We look forward to following his journey and the insights his work will bring to the field.

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