My PhD project explores whether the brain's immune cells, microglia, are involved in development of Alzheimer’s disease. With increasing age, some microglia start to accumulate lipids, which in time can make them function less efficiently. I study when these lipid-filled microglia appear, how they affect the cell’s ability to clean up waste and control inflammation, and whether improving their lipid-recycling systems can help them function normally again. The goal is to determine whether lipid dysregulation is a marker, a byproduct, or a  causal mechanism in Alzheimer’s progression.