Study opportunities

Hanne Poulsen's lab

Lab background:

For us to sense temperature - or light or sound or smell - the signal from the outside world has to be translated into an electrical signal that our neurons can interpret and react to. In the group, we study membrane proteins important for neuronal signaling and transport in order to understand their basic mechanisms and the physiological consequences it has if they do not function optimally.

Available projects:

How do we sense temperature?

Our bodies are very sensitive thermometers, and one of the key reasons is a group of ion channels called TRPs that respond to a change in temperature by opening and allowing cations to flow into the cell. It remains completely unknown how temperature can function as the key that opens a channel.

Other projects:

-understanding why CAPOS patients lose sight and hearing using a mouse model of the disease

-characterization of the GABA transporter using voltage-clamp fluorometry

-the role of the Na,K-ATPase in regulating inhibitory neuronal firing patterns

-investigating the regulation of glutamate receptors during memory formation


We use electrophysiological methods to study membrane proteins that produce a current when active, including voltage-clamp fluorometry, where protein movements are correlated with protein activity with millisecond resolution.

The successful applicant is:

Students with an interest in molecular biology and neuroscience with a background in natural sciences or medicine will be very welcome. Having taken neuroscience courses will be advantageous.

Please contact Team Leader Hanne Poulsen directly, if interested.