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2014.06.27 | Research news, PoulHenningJensen

New publication from Poul Henning Jensen's group - DJ-1 interactions with alpha-synuclein attenuate aggregation and cellular toxicity in models of Parkinson's disease

Alpha-synuclein and DJ-1 are key players in Parkinson disease possessing opposing effects with alpha-synuclein harming and DJ-1 protecting cells. We found that DJ-1 directly interact with alpha-synuclein thereby attenuating its toxic effect. The study is in collaboration with University Medical Center Göttingen and University of Leicester.

2014.06.27 | Research news, AndersNykjær

Growing pains in the brain's reward system can lead to ADHD

New research from Anders Nykjær's group at Aarhus University and one of the world's leading hospitals contributes to the understanding of ADHD. Experiments on mice show how the incorrect branching of nerve cells in the brain’s reward system leads to behavioural disorders.

2014.06.13 | Research news, AndersNykjær

New publication - SorCS2 Regulates Dopaminergic Wiring and Is Processed into an Apoptotic Two-Chain Receptor in Peripheral Glia

New publication from Anders Nykjær's group in collaboration with the private American hospital The Mayo Clinic published in the journal Neuron. The new research findings increase our understanding of why the neuropsychiatric disorder ADHD occurs in the brain.

2014.06.12 | Events

INNOVATE, PROTECT, SPIN IT OFF AND START IT UP! - New course at the Finnish EMBL node (FIMM)

The Institute for Molecular Medicine Finland (FIMM), which is the Finnish node of the EMBL Partnership, announces this interesting course from 23-25 September 2014 in Biomedicum, Helsinki, Finland. The topics covered are IPR, innovation and entrepreneurship, biotech and spin-off companies and marketing. Interested DANDRITE researchers can contact…

2014.06.06 | Events

DANDRITE Seminar - 12 June 2014

DANDRITE Seminar "Structural Insights into the Gating of a Pentameric Ligand-Gated Ion Channel" by visitor Azadeh Shahsavar on Thursday 12 June 2014 from 13.15 – 14.00 in the conference room (3130-303), Gustav Wieds Vej 10C, 8000 Aarhus C. Azadeh Shahsavar comes from the Dept. Drug Design and Pharmacology, University of Copenhagen, and is visiting…

2014.06.06 | Research news, PoulHenningJensen

New publication - How epigallocatechin gallate can inhibit alpha-synuclein oligomer toxicity in vitro

New publication from Poul Henning Jensen's group in collaboration with prof. Daniel Otzen's group at iNANO published in The Journal of Biological Chemistry. This study investigated how the flavonoid epigallocatechin gallate protects against alpha-synuclein oligomer cytotoxicity that forms in Parkinson's disease.