BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//TYPO3/NONSGML News system (news)//EN
BEGIN:VEVENT
UID:news-19990@dandrite.au.dk
DTSTAMP:20220112T103015Z
DTSTART:20210407T100000Z
DTEND:20210407T110000Z
END:VEVENT
END:VCALENDAR




<div class="news news-single">
	<div class="article" itemscope="itemscope" itemtype="http://schema.org/Article">
		
	
			<script type="text/javascript">
				const showAllContentLangToken = "Show all content ";
			</script>

			
			

			<article class="typo3-delphinus delphinus-gutters">

				<!-- News PID: 9479 - used for finding folder/page which contains the news / event -->
				<!-- News UID: 19990 - the ID of the current news / event-->

				<div class="news-event">
					<div class="news-event__header">
						<!-- Categories -->
						
							<span class="text--stamp">
<!-- categories -->
<span class="news-list-category">
	
		
	
		
	
		
	
		
	
</span>

</span>
						

						<!-- Title -->
						<h1 itemprop="headline">Biomedicine Seminar by Per Borghammer</h1>
						
							<!-- Teaser -->
							<p class="text--intro" itemprop="description">Prof. Per Borghammer from the Department of Nuclear Medicine &amp; PET at Aarhus University Hospital will held a Biomedicine Seminar entitled: "Parkinson's disease - motor asymmetry, dementia, and brain-first vs. body-first subtypes explained by prion-like spreading of alpha-synuclein"</p>
						
					</div>

					

					<div class="news-event__content">

						<!-- Events info box -->
						
								

								<div class="news-event__info theme--dark" id="event-info">
									<h2 class="screenreader-only">Info about event</h2>

									
											<!--- Same date -->
											<div class="news-event__info__item news-event__info__item--time">
												<h3 class="news-event__info__item__header text--label-header">Time</h3>
												<div class="news-event__info__item__content">
													<span class="u-avoid-wrap">
														Wednesday  7  April 2021,
													</span>
													<span class="u-avoid-wrap">
														&nbsp;at 12:00 -  13:00
													</span>
													<p class="news-event__info__item__ical-link"><a href="/display/artikel/biomedicine-seminar-by-per-borghammer?tx_news_pi1%5Bformat%5D=ical&amp;type=9819&amp;cHash=5c5244c18a3fda5ea13466e32403b273">Add to calendar</a></p>
												</div>
											</div>
										

									<!-- Location detailed -->
									
											<!-- Location Simple -->
											
												<div class="news-event__info__item">
													<h3 class="news-event__info__item__header text--label-header">Location</h3>
													<div class="news-event__info__item__content">
														<p>Online via Zoom</p>
													</div>
												</div>
											
										

									<!-- Organizer detailed -->
									
											<!-- Organizer Simple -->
											
										

									<!-- Price -->
									

									<!-- Event link -->
									

									<!-- Registration -->
									
								</div>
							

						
							<!-- Media -->
							
								



							
						

						
							<div class="news-event__content__text">
								<span class="text--byline" id="byline">
									

									<!-- Author -->
									
										<span itemprop="author" itemscope="itemscope" itemtype="http://schema.org/Person">
											
													By
												

											
													<a href="mailto:karasmus@dandrite.au.dk">
														<span itemprop="name">Katrine Østerlund Rasmussen</span>
													</a>
												
										</span>
									
								</span>

								

									<!-- Body text -->
									<h4><strong>Abstract</strong></h4>
<p> Parkinson's disease (PD) is an extremely heterogeneous disorder with varying symptomatology among patients. The majority of cases display asymmetric motor symptoms and most cases eventually develop dementia. The underlying causes for this motor asymmetry, non-motor subtypes and differing progression rates towards dementia have never been satisfactorily explained. </p>
<p> This lecture covers the new&nbsp;<em>alpha-synuclein origin and connectome</em>&nbsp;(SOC) model of PD, recently proposed as a unifying theory to resolve those hitherto unexplained phenomena of PD. The model suggests that the initial misfolding and aggregation of alpha-synuclein occurs in a single location within the central or peripheral nervous system - leading to body-first PD if the first pathology arises in the peripheral nervous system and brain-first if the first pathology occurs in the CNS. The subsequent spreading of pathology is then dependent on the connectome, especially the predominantly ipsilateral connectivity of mammalian brains. Together, these details can explain why PD is often but not always an asymmetric disease, and why the temporal sequence of symptom development varies from patient to patient.&nbsp;&nbsp;</p>
<p>Recent open access paper on the SOC model:&nbsp;<a href="https://content.iospress.com/articles/journal-of-parkinsons-disease/jpd202481" target="_blank" rel="noreferrer">https://content.iospress.com/articles/journal-of-parkinsons-disease/jpd202481</a>&nbsp;</p>
<p><strong>Join Zoom Meeting:</strong>&nbsp;<br><a href="https://aarhusuniversity.zoom.us/j/63590142121" target="_self">https://aarhusuniversity.zoom.us/j/63590142121</a>&nbsp;</p>
								
							</div>
						
					</div>

					
						<!-- Content elements -->
						
					
				</div>
			</article>

			
				
				
			

			<!-- related things -->
			
		

	</div>
</div>