Movies

Movie of the Na+/K+-ATPase with ATP


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All rights reserved. Use of the movie should refer to Nyblom et al. 2013.


Please refer to the following papers for further details:

Crystal structure of Na+, K(+)-ATPase in the Na(+)-bound state.
Nyblom M, Poulsen H, Gourdon P, Reinhard L, Andersson M, Lindahl E, Fedosova N, Nissen P.
Science. 2013 Oct 4;342(6154):123-7.

Structures and characterization of digoxin- and bufalin-bound Na+,K+-ATPase compared with the ouabain-bound complex.
Laursen M, Gregersen JL, Yatime L, Nissen P, Fedosova NU.
Proc Natl Acad Sci U S A. 2015 Feb 10;112(6):1755-60.

Crystal structure of the high-affinity Na+K+-ATPase-ouabain complex with Mg2+ bound in the cation binding site.
Laursen M, Yatime L, Nissen P, Fedosova NU.
Proc Natl Acad Sci U S A. 2013 Jul 2;110(27):10958-63.

Crystal structure of the sodium-potassium pump.
Morth JP, Pedersen BP, Toustrup-Jensen MS, Sørensen TL, Petersen J, Andersen JP, Vilsen B, Nissen P.
Nature. 2007 Dec 13;450(7172):1043-9.

How to Compare, Analyze, and Morph Between Crystal Structures of Different Conformations : The P-Type ATPase Example.
Karlsen JL, Bublitz M.
Methods in molecular biology (Clifton, N.J.), Vol. 1377, 2016, s. 523-39.

 

Movie of SERCA with H+


Download movie file (mov. file, 5557 KB)

All rights reserved. Use of the movie should refer to Bublitz et al. 2013.


Please refer to the following papers for further details: 

How to Compare, Analyze, and Morph Between Crystal Structures of Different Conformations : The P-Type ATPase Example.
Karlsen JL, Bublitz M.
Methods in molecular biology (Clifton, N.J.), Vol. 1377, 2016, s. 523-39.

Ion pathways in the sarcoplasmic reticulum Ca2+-ATPase.
Bublitz M, Musgaard M, Poulsen H, Thøgersen L, Olesen C, Schiøtt B, Morth JP, Møller JV, Nissen P.
J Biol Chem. 2013 Apr 12;288(15):10759-65.

The sarcolipin-bound calcium pump stabilizes calcium sites exposed to the cytoplasm.
Winther AM, Bublitz M, Karlsen JL, Møller JV, Hansen JB, Nissen P, Buch-Pedersen MJ.
Nature. 2013 Mar 14;495(7440):265-9.

Mutual adaptation of a membrane protein and its lipid bilayer during conformational changes.
Sonntag Y, Musgaard M, Olesen C, Schiøtt B, Møller JV, Nissen P, Thøgersen L.
Nat Commun. 2011;2:304.

The sarcoplasmic Ca2+-ATPase: design of a perfect chemi-osmotic pump.
Møller JV, Olesen C, Winther AM, Nissen P.
Q Rev Biophys. 2010 Nov;43(4):501-66.

Cyclopiazonic acid is complexed to a divalent metal ion when bound to the sarcoplasmic reticulum Ca2+-ATPase.
Laursen M, Bublitz M, Moncoq K, Olesen C, Møller JV, Young HS, Nissen P, Morth JP.
J Biol Chem. 2009 May 15;284(20):13513-8.

Crystal structure of D351A and P312A mutant forms of the mammalian sarcoplasmic reticulum Ca(2+) -ATPase reveals key events in phosphorylation and Ca(2+) release.
Marchand A, Winther AM, Holm PJ, Olesen C, Montigny C, Arnou B, Champeil P, Clausen JD, Vilsen B, Andersen JP, Nissen P, Jaxel C, Møller JV, le Maire M.
J Biol Chem. 2008 May 23;283(21):14867-82.

The structural basis of calcium transport by the calcium pump.
Olesen C, Picard M, Winther AM, Gyrup C, Morth JP, Oxvig C, Møller JV, Nissen P.
Nature. 2007 Dec 13;450(7172):1036-42.

Modulatory and catalytic modes of ATP binding by the calcium pump.
Jensen AM, Sørensen TL, Olesen C, Møller JV, Nissen P.
EMBO J. 2006 Jun 7;25(11):2305-14. Epub 2006 May 18.

Dephosphorylation of the calcium pump coupled to counterion occlusion.
Olesen C, Sørensen TL, Nielsen RC, Møller JV, Nissen P.
Science. 2004 Dec 24;306(5705):2251-5.

Phosphoryl transfer and calcium ion occlusion in the calcium pump.
Sørensen TL, Møller JV, Nissen P.
Science. 2004 Jun 11;304(5677):1672-5.

Movie of SERCA with H+ in membrane


Download movie file (mov. file, 14,783 KB)

All rights reserved. Use of the movie should refer to Bublitz et al. 2013.


Please refer to the following papers for further details: 

How to Compare, Analyze, and Morph Between Crystal Structures of Different Conformations : The P-Type ATPase Example.
Karlsen JL, Bublitz M.
Methods in molecular biology (Clifton, N.J.), Vol. 1377, 2016, s. 523-39.

Ion pathways in the sarcoplasmic reticulum Ca2+-ATPase.
Bublitz M, Musgaard M, Poulsen H, Thøgersen L, Olesen C, Schiøtt B, Morth JP, Møller JV, Nissen P.
J Biol Chem. 2013 Apr 12;288(15):10759-65.

The sarcolipin-bound calcium pump stabilizes calcium sites exposed to the cytoplasm.
Winther AM, Bublitz M, Karlsen JL, Møller JV, Hansen JB, Nissen P, Buch-Pedersen MJ.
Nature. 2013 Mar 14;495(7440):265-9.

Mutual adaptation of a membrane protein and its lipid bilayer during conformational changes.
Sonntag Y, Musgaard M, Olesen C, Schiøtt B, Møller JV, Nissen P, Thøgersen L.
Nat Commun. 2011;2:304.

The sarcoplasmic Ca2+-ATPase: design of a perfect chemi-osmotic pump.
Møller JV, Olesen C, Winther AM, Nissen P.
Q Rev Biophys. 2010 Nov;43(4):501-66.

Cyclopiazonic acid is complexed to a divalent metal ion when bound to the sarcoplasmic reticulum Ca2+-ATPase.
Laursen M, Bublitz M, Moncoq K, Olesen C, Møller JV, Young HS, Nissen P, Morth JP.
J Biol Chem. 2009 May 15;284(20):13513-8.

Crystal structure of D351A and P312A mutant forms of the mammalian sarcoplasmic reticulum Ca(2+) -ATPase reveals key events in phosphorylation and Ca(2+) release.
Marchand A, Winther AM, Holm PJ, Olesen C, Montigny C, Arnou B, Champeil P, Clausen JD, Vilsen B, Andersen JP, Nissen P, Jaxel C, Møller JV, le Maire M.
J Biol Chem. 2008 May 23;283(21):14867-82.

The structural basis of calcium transport by the calcium pump.
Olesen C, Picard M, Winther AM, Gyrup C, Morth JP, Oxvig C, Møller JV, Nissen P.
Nature. 2007 Dec 13;450(7172):1036-42.

Modulatory and catalytic modes of ATP binding by the calcium pump.
Jensen AM, Sørensen TL, Olesen C, Møller JV, Nissen P.
EMBO J. 2006 Jun 7;25(11):2305-14. Epub 2006 May 18.

Dephosphorylation of the calcium pump coupled to counterion occlusion.
Olesen C, Sørensen TL, Nielsen RC, Møller JV, Nissen P.
Science. 2004 Dec 24;306(5705):2251-5.

Phosphoryl transfer and calcium ion occlusion in the calcium pump.
Sørensen TL, Møller JV, Nissen P.
Science. 2004 Jun 11;304(5677):1672-5.